BDBM50332142 (S)-2-(3-(hydroxymethyl)phenyl)-4-(piperidin-3-ylamino)thieno[3,2-c]pyridine-7-carboxamide::CHEMBL1288010

SMILES: NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccc(CO)c1

InChI Key: InChIKey=YNQHLQYVIDIBNI-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50332142 ((S)-2-(3-(hydroxymethyl)phenyl)-4-(piperidin-3-yla...) Show SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccc(CO)c1 |r| Show InChI InChI=1S/C20H22N4O2S/c21-19(26)16-10-23-20(24-14-5-2-6-22-9-14)15-8-17(27-18(15)16)13-4-1-3-12(7-13)11-25/h1,3-4,7-8,10,14,22,25H,2,5-6,9,11H2,(H2,21,26)(H,23,24)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 7216-21 (2010) Article DOI: 10.1016/j.bmcl.2010.10.105 BindingDB Entry DOI: 10.7270/Q2QV3MR6
					More data for this Ligand-Target Pair