BDBM50332165 (S)-2-(3-(N,N-dimethylsulfamoyl)phenyl)-4-(piperidin-3-ylamino)thieno[3,2-c]pyridine-7-carboxamide::CHEMBL1287893

SMILES: CN(C)S(=O)(=O)c1cccc(c1)-c1cc2c(N[C@H]3CCCNC3)ncc(C(N)=O)c2s1

InChI Key: InChIKey=WVIBVXYNASVWTL-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50332165 ((S)-2-(3-(N,N-dimethylsulfamoyl)phenyl)-4-(piperid...) Show SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1cc2c(N[C@H]3CCCNC3)ncc(C(N)=O)c2s1 |r| Show InChI InChI=1S/C21H25N5O3S2/c1-26(2)31(28,29)15-7-3-5-13(9-15)18-10-16-19(30-18)17(20(22)27)12-24-21(16)25-14-6-4-8-23-11-14/h3,5,7,9-10,12,14,23H,4,6,8,11H2,1-2H3,(H2,22,27)(H,24,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 7216-21 (2010) Article DOI: 10.1016/j.bmcl.2010.10.105 BindingDB Entry DOI: 10.7270/Q2QV3MR6
					More data for this Ligand-Target Pair