BDBM50332273 (R)-2-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzamide::CHEMBL1288182

SMILES: COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3C(N)=O)C(=O)c2c1

InChI Key: InChIKey=NWWNIDJIHDZVFT-JOCHJYFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50332273 ((R)-2-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)...) Show SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3C(N)=O)C(=O)c2c1 |r| Show InChI InChI=1S/C22H18N4O5/c1-31-15-7-6-14-11-26(19(28)17(14)10-15)12-22(20(29)24-21(30)25-22)9-8-13-4-2-3-5-16(13)18(23)27/h2-7,10H,11-12H2,1H3,(H2,23,27)(H2,24,25,29,30)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 20: 7283-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.081 BindingDB Entry DOI: 10.7270/Q2Z89CP0
					More data for this Ligand-Target Pair