BDBM50332338 3-(4-(methylsulfonyl)phenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1632406

SMILES: Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=UISAGCHZHVJOQK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50332338 (3-(4-(methylsulfonyl)phenyl)-5-p-tolyl-4,5-dihydro...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(cc1)S(C)(=O)=O |c:10| Show InChI InChI=1S/C18H19N3O2S2/c1-12-3-5-14(6-4-12)17-11-16(20-21(17)18(19)24)13-7-9-15(10-8-13)25(2,22)23/h3-10,17H,11H2,1-2H3,(H2,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 expressed in baculovirus infected SF21 cell				Eur J Med Chem 45: 6135-8 (2010) Article DOI: 10.1016/j.ejmech.2010.10.005 BindingDB Entry DOI: 10.7270/Q2PV6KMT
					More data for this Ligand-Target Pair