BDBM50332339 5-(4-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1629743

SMILES: CS(=O)(=O)c1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)C(N)=S

InChI Key: InChIKey=BZNFRRPUMXAVHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50332339 (5-(4-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)-4,...) Show SMILES CS(=O)(=O)c1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)C(N)=S |t:11| Show InChI InChI=1S/C17H16ClN3O2S2/c1-25(22,23)14-8-4-11(5-9-14)15-10-16(21(20-15)17(19)24)12-2-6-13(18)7-3-12/h2-9,16H,10H2,1H3,(H2,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 expressed in baculovirus infected SF21 cell				Eur J Med Chem 45: 6135-8 (2010) Article DOI: 10.1016/j.ejmech.2010.10.005 BindingDB Entry DOI: 10.7270/Q2PV6KMT
					More data for this Ligand-Target Pair