BDBM50332342 1-(5-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone::CHEMBL1632400

SMILES: COc1ccc(cc1)C1CC(=NN1C(C)=O)c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=UYIIURKRIHGLNP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50332342 (1-(5-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl...) Show SMILES COc1ccc(cc1)C1CC(=NN1C(C)=O)c1ccc(cc1)S(C)(=O)=O |c:11| Show InChI InChI=1S/C19H20N2O4S/c1-13(22)21-19(15-4-8-16(25-2)9-5-15)12-18(20-21)14-6-10-17(11-7-14)26(3,23)24/h4-11,19H,12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 expressed in baculovirus infected SF21 cell				Eur J Med Chem 45: 6135-8 (2010) Article DOI: 10.1016/j.ejmech.2010.10.005 BindingDB Entry DOI: 10.7270/Q2PV6KMT
					More data for this Ligand-Target Pair