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SMILES: COc1ccc(cc1)-c1cc([nH]c(=O)c1O)-c1ccc(F)cc1

InChI Key: InChIKey=HOXWPBSKWPOBQZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332537   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50332537
PNG
(6-(4-fluorophenyl)-3-hydroxy-4-(4-methoxyphenyl)py...)
Show SMILES COc1ccc(cc1)-c1cc([nH]c(=O)c1O)-c1ccc(F)cc1
Show InChI InChI=1S/C18H14FNO3/c1-23-14-8-4-11(5-9-14)15-10-16(20-18(22)17(15)21)12-2-6-13(19)7-3-12/h2-10,21H,1H3,(H,20,22)
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PC cid
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Article
PubMed
n/an/a 325n/an/an/an/an/an/a



University of Louisiana at Monroe

Curated by ChEMBL


Assay Description
Inhibition of recombinant GSK3beta Z'-LYTE kinase assay kit method

J Med Chem 53: 8534-45 (2010)


Article DOI: 10.1021/jm100941j
BindingDB Entry DOI: 10.7270/Q2DB8230
More data for this
Ligand-Target Pair