BDBM50332647 1-(2'-fluoro-6'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide::CHEMBL1631098

SMILES: NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1c(F)cccc1OC(F)(F)F

InChI Key: InChIKey=HGMBLKLOKFTAOU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50332647 (1-(2'-fluoro-6'-(trifluoromethoxy)biphenyl-3-yl)-1...) Show SMILES NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1c(F)cccc1OC(F)(F)F Show InChI InChI=1S/C18H12F4N4O3/c19-11-5-2-6-14(29-18(20,21)22)15(11)9-3-1-4-10(7-9)26-13(17(24)28)8-12(25-26)16(23)27/h1-8H,(H2,23,27)(H2,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	802	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50332647 (1-(2'-fluoro-6'-(trifluoromethoxy)biphenyl-3-yl)-1...) Show SMILES NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1c(F)cccc1OC(F)(F)F Show InChI InChI=1S/C18H12F4N4O3/c19-11-5-2-6-14(29-18(20,21)22)15(11)9-3-1-4-10(7-9)26-13(17(24)28)8-12(25-26)16(23)27/h1-8H,(H2,23,27)(H2,24,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair