BDBM50332648 1-(2'-(trifluoromethoxy)-5'-(trifluoromethyl)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide::CHEMBL1631099

SMILES: NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1cc(ccc1OC(F)(F)F)C(F)(F)F

InChI Key: InChIKey=JNPMBTFQNYBLOP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332648   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50332648 (1-(2'-(trifluoromethoxy)-5'-(trifluoromethyl)biphe...) Show SMILES NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1cc(ccc1OC(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H12F6N4O3/c20-18(21,22)10-4-5-15(32-19(23,24)25)12(7-10)9-2-1-3-11(6-9)29-14(17(27)31)8-13(28-29)16(26)30/h1-8H,(H2,26,30)(H2,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50332648 (1-(2'-(trifluoromethoxy)-5'-(trifluoromethyl)biphe...) Show SMILES NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1cc(ccc1OC(F)(F)F)C(F)(F)F Show InChI InChI=1S/C19H12F6N4O3/c20-18(21,22)10-4-5-15(32-19(23,24)25)12(7-10)9-2-1-3-11(6-9)29-14(17(27)31)8-13(28-29)16(26)30/h1-8H,(H2,26,30)(H2,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair