BDBM50332653 5-methyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3,4-dicarboxamide::CHEMBL1631086

SMILES: Cc1c(C(N)=O)c(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O

InChI Key: InChIKey=BKGRPPQRGSQIIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50332653 (5-methyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H...) Show SMILES Cc1c(C(N)=O)c(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O Show InChI InChI=1S/C19H15F3N4O3/c1-10-15(17(23)27)16(18(24)28)25-26(10)12-6-4-5-11(9-12)13-7-2-3-8-14(13)29-19(20,21)22/h2-9H,1H3,(H2,23,27)(H2,24,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair