BDBM50332654 1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3,4,5-tricarboxamide::CHEMBL1631087

SMILES: NC(=O)c1nn(c(C(N)=O)c1C(N)=O)-c1cccc(c1)-c1ccccc1OC(F)(F)F

InChI Key: InChIKey=TYFJSISVIKFMMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50332654 (1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole...) Show SMILES NC(=O)c1nn(c(C(N)=O)c1C(N)=O)-c1cccc(c1)-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C19H14F3N5O4/c20-19(21,22)31-12-7-2-1-6-11(12)9-4-3-5-10(8-9)27-15(18(25)30)13(16(23)28)14(26-27)17(24)29/h1-8H,(H2,23,28)(H2,24,29)(H2,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair