BDBM50332662 1-(4'-fluoro-2'-(2,2,3,3,3-pentafluoropropoxy)biphenyl-3-yl)-1H-pyrazole-3,5-dicarboxamide::CHEMBL1631101
SMILES: NC(=O)c1cc(C(N)=O)n(n1)-c1cccc(c1)-c1ccc(F)cc1OCC(F)(F)C(F)(F)F
InChI Key: InChIKey=WISFZHDUKWADFP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium channel protein type 9 subunit alpha (Homo sapiens (Human)) | BDBM50332662 (1-(4'-fluoro-2'-(2,2,3,3,3-pentafluoropropoxy)biph...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human Nav1.7 by VIPR assay | Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH | |||||||||||
More data for this Ligand-Target Pair |