BDBM50332769 (R)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::CHEMBL1630249

SMILES: CCCc1cc2O[C@H](C(=Cc2cc1Cl)C(O)=O)C(F)(F)F

InChI Key: InChIKey=ADUDQKMQQHYYGO-GFCCVEGCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50332769 ((R)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...) Show SMILES CCCc1cc2O[C@H](C(=Cc2cc1Cl)C(O)=O)C(F)(F)F |r,c:8| Show InChI InChI=1S/C14H12ClF3O3/c1-2-3-7-6-11-8(5-10(7)15)4-9(13(19)20)12(21-11)14(16,17)18/h4-6,12H,2-3H2,1H3,(H,19,20)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human COX2				Bioorg Med Chem Lett 20: 7159-63 (2010) Article DOI: 10.1016/j.bmcl.2010.07.054 BindingDB Entry DOI: 10.7270/Q23X86W1
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50332769 ((R)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...) Show SMILES CCCc1cc2O[C@H](C(=Cc2cc1Cl)C(O)=O)C(F)(F)F |r,c:8| Show InChI InChI=1S/C14H12ClF3O3/c1-2-3-7-6-11-8(5-10(7)15)4-9(13(19)20)12(21-11)14(16,17)18/h4-6,12H,2-3H2,1H3,(H,19,20)/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human COX1				Bioorg Med Chem Lett 20: 7159-63 (2010) Article DOI: 10.1016/j.bmcl.2010.07.054 BindingDB Entry DOI: 10.7270/Q23X86W1
					More data for this Ligand-Target Pair