BDBM50332793 2,6-Dibenzyl-4-(5-nitro-furan-2-ylm ethylene)-1,1-dioxo-1lambda*6*-[1,2 ,6]thiadiazinane-3,5-dione::CHEMBL1630897

SMILES: [#8-]-[#7+](=O)-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7](-[#6]-c3ccccc3)S(=O)(=O)[#7](-[#6]-c3ccccc3)-[#6]-2=O)o1

InChI Key: InChIKey=IAFAANQPDPWPHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332793 (2,6-Dibenzyl-4-(5-nitro-furan-2-ylm ethylene)-1,1-...) Show SMILES [#8-]-[#7+](=O)-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7](-[#6]-c3ccccc3)S(=O)(=O)[#7](-[#6]-c3ccccc3)-[#6]-2=O)o1 Show InChI InChI=1S/C22H17N3O7S/c26-21-19(13-18-11-12-20(32-18)25(28)29)22(27)24(15-17-9-5-2-6-10-17)33(30,31)23(21)14-16-7-3-1-4-8-16/h1-13H,14-15H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
					More data for this Ligand-Target Pair