BDBM50332796 5-phenyl-1,3,4-oxathiazol-2-one::CHEMBL1632533

SMILES: O=c1oc(ns1)-c1ccccc1

InChI Key: InChIKey=NDAURKDIFHXVHE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
26S proteosome (Homo sapiens (Human))	BDBM50332796 (5-phenyl-1,3,4-oxathiazol-2-one | CHEMBL1632533) Show SMILES O=c1oc(ns1)-c1ccccc1 Show InChI InChI=1S/C8H5NO2S/c10-8-11-7(9-12-8)6-4-2-1-3-5-6/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 min...				ACS Med Chem Lett 5: 405-10 (2014) Article DOI: 10.1021/ml400531d BindingDB Entry DOI: 10.7270/Q2PZ5BCF
					More data for this Ligand-Target Pair
Triosephosphate isomerase, glycosomal (Trypanosoma cruzi)	BDBM50332796 (5-phenyl-1,3,4-oxathiazol-2-one | CHEMBL1632533) Show SMILES O=c1oc(ns1)-c1ccccc1 Show InChI InChI=1S/C8H5NO2S/c10-8-11-7(9-12-8)6-4-2-1-3-5-6/h1-5H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de la Rep£blica Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi triosephosphate isomerase after 2 hrs				Eur J Med Chem 45: 5767-72 (2010) Article DOI: 10.1016/j.ejmech.2010.09.034 BindingDB Entry DOI: 10.7270/Q2QN6719
					More data for this Ligand-Target Pair