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BDBM50332834 CHEMBL1630292::syn(2S,5'R)-(-)-3-Methoxy-5-pyrrolidin-2-yl-4,5-dihydroisoxazole

SMILES: COC1=NO[C@H](C1)[C@@H]1CCCN1

InChI Key: InChIKey=IWHMHIGCZDANJP-NKWVEPMBSA-N

Data: 2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332834
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50332834 (CHEMBL1630292 \| syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...) Show SMILES COC1=NO[C@H](C1)[C@@H]1CCCN1 \|r,t:2\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta counting				Eur J Med Chem 45: 5594-601 (2010) Article DOI: 10.1016/j.ejmech.2010.09.009 BindingDB Entry DOI: 10.7270/Q2BC3ZSJ
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50332834 (CHEMBL1630292 \| syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...) Show SMILES COC1=NO[C@H](C1)[C@@H]1CCCN1 \|r,t:2\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.77E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma counting				Eur J Med Chem 45: 5594-601 (2010) Article DOI: 10.1016/j.ejmech.2010.09.009 BindingDB Entry DOI: 10.7270/Q2BC3ZSJ
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair