BDBM50332837 CHEMBL1630295::anti(2S,5'S)-(+)-3-tert-butoxy-5-pyrrolidin-2-yl-4,5-dihydroisoxazole

SMILES: CC(C)(C)OC1=NO[C@@H](C1)[C@@H]1CCCN1

InChI Key: InChIKey=LAUIYVZDKSCUAB-IUCAKERBSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50332837 (CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...) Show SMILES CC(C)(C)OC1=NO[C@@H](C1)[C@@H]1CCCN1 |r,t:5| Show InChI InChI=1S/C11H20N2O2/c1-11(2,3)14-10-7-9(15-13-10)8-5-4-6-12-8/h8-9,12H,4-7H2,1-3H3/t8-,9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.84E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta counting				Eur J Med Chem 45: 5594-601 (2010) Article DOI: 10.1016/j.ejmech.2010.09.009 BindingDB Entry DOI: 10.7270/Q2BC3ZSJ
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50332837 (CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...) Show SMILES CC(C)(C)OC1=NO[C@@H](C1)[C@@H]1CCCN1 |r,t:5| Show InChI InChI=1S/C11H20N2O2/c1-11(2,3)14-10-7-9(15-13-10)8-5-4-6-12-8/h8-9,12H,4-7H2,1-3H3/t8-,9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma counting				Eur J Med Chem 45: 5594-601 (2010) Article DOI: 10.1016/j.ejmech.2010.09.009 BindingDB Entry DOI: 10.7270/Q2BC3ZSJ
					More data for this Ligand-Target Pair