BDBM50333118 CHEMBL4176751

SMILES: NCc1cccc(c1)-c1cccc(NC(=O)CCc2ccccc2)c1

InChI Key: InChIKey=MWOUCVQIGQKXGO-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM50333118 (CHEMBL4176751) Show SMILES NCc1cccc(c1)-c1cccc(NC(=O)CCc2ccccc2)c1 Show InChI InChI=1S/C22H22N2O/c23-16-18-8-4-9-19(14-18)20-10-5-11-21(15-20)24-22(25)13-12-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16,23H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM50333118 (CHEMBL4176751) Show SMILES NCc1cccc(c1)-c1cccc(NC(=O)CCc2ccccc2)c1 Show InChI InChI=1S/C22H22N2O/c23-16-18-8-4-9-19(14-18)20-10-5-11-21(15-20)24-22(25)13-12-17-6-2-1-3-7-17/h1-11,14-15H,12-13,16,23H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by s...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair