BDBM50333160 9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione::CHEMBL1644823

SMILES: Cc1ccc2[nH]c(=O)n3c(nn(-c4ccccc4)c3=O)c2c1

InChI Key: InChIKey=OGBTVLIUFUJHTH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50333160 (9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...) Show SMILES Cc1ccc2[nH]c(=O)n3c(nn(-c4ccccc4)c3=O)c2c1 Show InChI InChI=1S/C16H12N4O2/c1-10-7-8-13-12(9-10)14-18-20(11-5-3-2-4-6-11)16(22)19(14)15(21)17-13/h2-9H,1H3,(H,17,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil human recombinant alpha1beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...				Bioorg Med Chem 19: 111-21 (2011) Article DOI: 10.1016/j.bmc.2010.11.050 BindingDB Entry DOI: 10.7270/Q2Z038FK
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50333160 (9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...) Show SMILES Cc1ccc2[nH]c(=O)n3c(nn(-c4ccccc4)c3=O)c2c1 Show InChI InChI=1S/C16H12N4O2/c1-10-7-8-13-12(9-10)14-18-20(11-5-3-2-4-6-11)16(22)19(14)15(21)17-13/h2-9H,1H3,(H,17,21)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil human recombinant alpha2beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...				Bioorg Med Chem 19: 111-21 (2011) Article DOI: 10.1016/j.bmc.2010.11.050 BindingDB Entry DOI: 10.7270/Q2Z038FK
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50333160 (9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...) Show SMILES Cc1ccc2[nH]c(=O)n3c(nn(-c4ccccc4)c3=O)c2c1 Show InChI InChI=1S/C16H12N4O2/c1-10-7-8-13-12(9-10)14-18-20(11-5-3-2-4-6-11)16(22)19(14)15(21)17-13/h2-9H,1H3,(H,17,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lund University Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil human recombinant alpha3beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...				Bioorg Med Chem 19: 111-21 (2011) Article DOI: 10.1016/j.bmc.2010.11.050 BindingDB Entry DOI: 10.7270/Q2Z038FK
					More data for this Ligand-Target Pair