BDBM50333504 1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)-3-cyclopentylurea::CHEMBL1641821

SMILES: O=C(NC1CCCC1)Nc1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=UEPMBFDUHOWDCI-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Mus musculus)	BDBM50333504 (1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-y...) Show SMILES O=C(NC1CCCC1)Nc1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C18H30N6OS/c25-16(19-14-6-2-3-7-14)20-17-21-22-18(26-17)24-12-8-15(9-13-24)23-10-4-1-5-11-23/h14-15H,1-13H2,(H2,19,20,21,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from mouse recombinant histamine H3 receptor after 30 mins by scintillation counting				ACS Med Chem Lett 3: 198-202 (2012) Article DOI: 10.1021/ml200250t BindingDB Entry DOI: 10.7270/Q2736S0M
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50333504 (1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-y...) Show SMILES O=C(NC1CCCC1)Nc1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C18H30N6OS/c25-16(19-14-6-2-3-7-14)20-17-21-22-18(26-17)24-12-8-15(9-13-24)23-10-4-1-5-11-23/h14-15H,1-13H2,(H2,19,20,21,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...				Bioorg Med Chem Lett 21: 861-4 (2011) Article DOI: 10.1016/j.bmcl.2010.11.065 BindingDB Entry DOI: 10.7270/Q20V8D24
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50333504 (1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-y...) Show SMILES O=C(NC1CCCC1)Nc1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C18H30N6OS/c25-16(19-14-6-2-3-7-14)20-17-21-22-18(26-17)24-12-8-15(9-13-24)23-10-4-1-5-11-23/h14-15H,1-13H2,(H2,19,20,21,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor after 30 mins by scintillation counting				ACS Med Chem Lett 3: 198-202 (2012) Article DOI: 10.1021/ml200250t BindingDB Entry DOI: 10.7270/Q2736S0M
					More data for this Ligand-Target Pair