BDBM50333507 3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)benzonitrile::CHEMBL1641824

SMILES: N#Cc1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=YNHBOTILBUGDPS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50333507 (3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-y...) Show SMILES N#Cc1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C19H23N5S/c20-14-15-5-4-6-16(13-15)18-21-22-19(25-18)24-11-7-17(8-12-24)23-9-2-1-3-10-23/h4-6,13,17H,1-3,7-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	42.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...				Bioorg Med Chem Lett 21: 861-4 (2011) Article DOI: 10.1016/j.bmcl.2010.11.065 BindingDB Entry DOI: 10.7270/Q20V8D24
					More data for this Ligand-Target Pair