BindingDB logo
myBDB logout

BDBM50333511 1-(3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)phenyl)ethanone::CHEMBL1641828

SMILES: CC(=O)c1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=MFTIZYIOACEQCN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333511   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50333511
PNG
(1-(3-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-...)
Show SMILES CC(=O)c1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C20H26N4OS/c1-15(25)16-6-5-7-17(14-16)19-21-22-20(26-19)24-12-8-18(9-13-24)23-10-3-2-4-11-23/h5-7,14,18H,2-4,8-13H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...

Bioorg Med Chem Lett 21: 861-4 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.065
BindingDB Entry DOI: 10.7270/Q20V8D24
More data for this
Ligand-Target Pair