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SMILES: COc1cccc(n1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=MXQPVUOHIDIHQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333520   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50333520
PNG
(2-(1,4'-bipiperidin-1'-yl)-5-(6-methoxypyridin-2-y...)
Show SMILES COc1cccc(n1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C18H25N5OS/c1-24-16-7-5-6-15(19-16)17-20-21-18(25-17)23-12-8-14(9-13-23)22-10-3-2-4-11-22/h5-7,14H,2-4,8-13H2,1H3
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Similars
Article
PubMed
 3.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation count...

Bioorg Med Chem Lett 21: 861-4 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.065
BindingDB Entry DOI: 10.7270/Q20V8D24
More data for this
Ligand-Target Pair