null

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ncc(s2)-c2ccco2)c1

InChI Key: InChIKey=UIGXMDHXJHVCRH-QSWMPLQWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50333628 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-2-yl)thi...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ncc(s2)-c2ccco2)c1 |r| Show InChI InChI=1S/C20H20ClNO6S/c21-12-4-3-10(20-19(26)18(25)17(24)14(9-23)28-20)6-11(12)7-16-22-8-15(29-16)13-2-1-5-27-13/h1-6,8,14,17-20,23-26H,7,9H2/t14-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counting				ACS Med Chem Lett 2: 182-187 (2011) Article DOI: 10.1021/ml100256c BindingDB Entry DOI: 10.7270/Q2959HVZ
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50333628 ((2S,3R,4R,5S,6R)-2-(4-Chloro-3-((5-(furan-2-yl)thi...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ncc(s2)-c2ccco2)c1 |r| Show InChI InChI=1S/C20H20ClNO6S/c21-12-4-3-10(20-19(26)18(25)17(24)14(9-23)28-20)6-11(12)7-16-22-8-15(29-16)13-2-1-5-27-13/h1-6,8,14,17-20,23-26H,7,9H2/t14-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75	n/a	n/a	n/a	n/a	n/a	n/a
Green Cross Corporation Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...				Bioorg Med Chem Lett 21: 742-6 (2011) Article DOI: 10.1016/j.bmcl.2010.11.115 BindingDB Entry DOI: 10.7270/Q2C24WPZ
					More data for this Ligand-Target Pair