BDBM50333849 (R)-2-(7-(N-(cyclopropylmethyl)-4-fluorophenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643788

SMILES: OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC1CC1)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=ONYPZLDHENOVTO-GOSISDBHSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333849 ((R)-2-(7-(N-(cyclopropylmethyl)-4-fluorophenylsulf...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC1CC1)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H25FN2O4S/c25-17-7-10-19(11-8-17)32(30,31)27(14-16-5-6-16)18-9-12-23-21(13-24(28)29)20-3-1-2-4-22(20)26(23)15-18/h1-4,7-8,10-11,16,18H,5-6,9,12-15H2,(H,28,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50333849 ((R)-2-(7-(N-(cyclopropylmethyl)-4-fluorophenylsulf...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC1CC1)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H25FN2O4S/c25-17-7-10-19(11-8-17)32(30,31)27(14-16-5-6-16)18-9-12-23-21(13-24(28)29)20-3-1-2-4-22(20)26(23)15-18/h1-4,7-8,10-11,16,18H,5-6,9,12-15H2,(H,28,29)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to prostanoid DP1 receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50333849 ((R)-2-(7-(N-(cyclopropylmethyl)-4-fluorophenylsulf...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC1CC1)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H25FN2O4S/c25-17-7-10-19(11-8-17)32(30,31)27(14-16-5-6-16)18-9-12-23-21(13-24(28)29)20-3-1-2-4-22(20)26(23)15-18/h1-4,7-8,10-11,16,18H,5-6,9,12-15H2,(H,28,29)/t18-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to thromboxane receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333849 ((R)-2-(7-(N-(cyclopropylmethyl)-4-fluorophenylsulf...) Show SMILES OC(=O)Cc1c2CC[C@H](Cn2c2ccccc12)N(CC1CC1)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H25FN2O4S/c25-17-7-10-19(11-8-17)32(30,31)27(14-16-5-6-16)18-9-12-23-21(13-24(28)29)20-3-1-2-4-22(20)26(23)15-18/h1-4,7-8,10-11,16,18H,5-6,9,12-15H2,(H,28,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair