BDBM50333875 (R)-2-(3-cyano-7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643776

SMILES: CN([C@@H]1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C#N)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=WAOXAIPADUUGNA-MRXNPFEDSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333875 ((R)-2-(3-cyano-7-(4-fluoro-N-methylphenylsulfonami...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C#N)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20FN3O4S/c1-25(31(29,30)17-6-3-15(23)4-7-17)16-5-9-20-19(11-22(27)28)18-8-2-14(12-24)10-21(18)26(20)13-16/h2-4,6-8,10,16H,5,9,11,13H2,1H3,(H,27,28)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50333875 ((R)-2-(3-cyano-7-(4-fluoro-N-methylphenylsulfonami...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C#N)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20FN3O4S/c1-25(31(29,30)17-6-3-15(23)4-7-17)16-5-9-20-19(11-22(27)28)18-8-2-14(12-24)10-21(18)26(20)13-16/h2-4,6-8,10,16H,5,9,11,13H2,1H3,(H,27,28)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to prostanoid DP1 receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50333875 ((R)-2-(3-cyano-7-(4-fluoro-N-methylphenylsulfonami...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C#N)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20FN3O4S/c1-25(31(29,30)17-6-3-15(23)4-7-17)16-5-9-20-19(11-22(27)28)18-8-2-14(12-24)10-21(18)26(20)13-16/h2-4,6-8,10,16H,5,9,11,13H2,1H3,(H,27,28)/t16-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>7.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to thromboxane receptor				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50333875 ((R)-2-(3-cyano-7-(4-fluoro-N-methylphenylsulfonami...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccc(cc3n2C1)C#N)S(=O)(=O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C22H20FN3O4S/c1-25(31(29,30)17-6-3-15(23)4-7-17)16-5-9-20-19(11-22(27)28)18-8-2-14(12-24)10-21(18)26(20)13-16/h2-4,6-8,10,16H,5,9,11,13H2,1H3,(H,27,28)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...				Bioorg Med Chem Lett 21: 288-93 (2010) Article DOI: 10.1016/j.bmcl.2010.11.015 BindingDB Entry DOI: 10.7270/Q2959HTH
					More data for this Ligand-Target Pair