null
SMILES: CC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc(sc1F)C(=O)N[C@H](CC(O)=O)c1ccccc1
InChI Key: InChIKey=ZRKGOWPEUYUOLZ-XMMPIXPASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50333941 ((R)-3-(4-(4'-acetylbiphenyl-4-yl)-5-fluorothiophen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec OAI Curated by ChEMBL | Assay Description Inhibition of MMP-12 catalytic domain | Bioorg Med Chem Lett 21: 528-30 (2010) Article DOI: 10.1016/j.bmcl.2010.10.087 BindingDB Entry DOI: 10.7270/Q2NC61G8 | |||||||||||
More data for this Ligand-Target Pair |