BDBM50333958 CHEMBL1644475::exo-(1R,5S)-3-(2-chlorophenoxy)-8-azabicyclo[3.2.1]octane

SMILES: Clc1ccccc1O[C@H]1C[C@@H]2CC[C@H](C1)N2

InChI Key: InChIKey=MJWXDPDEDHUUJV-JGPRNRPPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50333958 (CHEMBL1644475 | exo-(1R,5S)-3-(2-chlorophenoxy)-8-...) Show SMILES Clc1ccccc1O[C@H]1C[C@@H]2CC[C@H](C1)N2 |r| Show InChI InChI=1S/C13H16ClNO/c14-12-3-1-2-4-13(12)16-11-7-9-5-6-10(8-11)15-9/h1-4,9-11,15H,5-8H2/t9-,10+,11-	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50333958 (CHEMBL1644475 | exo-(1R,5S)-3-(2-chlorophenoxy)-8-...) Show SMILES Clc1ccccc1O[C@H]1C[C@@H]2CC[C@H](C1)N2 |r| Show InChI InChI=1S/C13H16ClNO/c14-12-3-1-2-4-13(12)16-11-7-9-5-6-10(8-11)15-9/h1-4,9-11,15H,5-8H2/t9-,10+,11-	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50333958 (CHEMBL1644475 | exo-(1R,5S)-3-(2-chlorophenoxy)-8-...) Show SMILES Clc1ccccc1O[C@H]1C[C@@H]2CC[C@H](C1)N2 |r| Show InChI InChI=1S/C13H16ClNO/c14-12-3-1-2-4-13(12)16-11-7-9-5-6-10(8-11)15-9/h1-4,9-11,15H,5-8H2/t9-,10+,11-	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	881	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation counting				Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3
					More data for this Ligand-Target Pair