Found 5 hits for monomerid = 50333996 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50333996
(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)Show SMILES O=c1n(nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1)C1CCOC1 Show InChI InChI=1S/C26H27N5O3/c32-26-30(22-6-5-18-3-1-2-4-19(18)15-22)25(29-31(26)23-10-14-34-17-23)20-7-11-27-24(16-20)28-21-8-12-33-13-9-21/h1-7,11,15-16,21,23H,8-10,12-14,17H2,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 315-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.010 BindingDB Entry DOI: 10.7270/Q24F1R0T |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 10
(Homo sapiens (Human)) | BDBM50333996
(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)Show SMILES O=c1n(nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1)C1CCOC1 Show InChI InChI=1S/C26H27N5O3/c32-26-30(22-6-5-18-3-1-2-4-19(18)15-22)25(29-31(26)23-10-14-34-17-23)20-7-11-27-24(16-20)28-21-8-12-33-13-9-21/h1-7,11,15-16,21,23H,8-10,12-14,17H2,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 315-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.010 BindingDB Entry DOI: 10.7270/Q24F1R0T |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 14
(Homo sapiens (Human)) | BDBM50333996
(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)Show SMILES O=c1n(nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1)C1CCOC1 Show InChI InChI=1S/C26H27N5O3/c32-26-30(22-6-5-18-3-1-2-4-19(18)15-22)25(29-31(26)23-10-14-34-17-23)20-7-11-27-24(16-20)28-21-8-12-33-13-9-21/h1-7,11,15-16,21,23H,8-10,12-14,17H2,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant p38alpha after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 315-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.010 BindingDB Entry DOI: 10.7270/Q24F1R0T |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50333996
(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)Show SMILES O=c1n(nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1)C1CCOC1 Show InChI InChI=1S/C26H27N5O3/c32-26-30(22-6-5-18-3-1-2-4-19(18)15-22)25(29-31(26)23-10-14-34-17-23)20-7-11-27-24(16-20)28-21-8-12-33-13-9-21/h1-7,11,15-16,21,23H,8-10,12-14,17H2,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant ERK2 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 315-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.010 BindingDB Entry DOI: 10.7270/Q24F1R0T |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50333996
(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)Show SMILES O=c1n(nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1)C1CCOC1 Show InChI InChI=1S/C26H27N5O3/c32-26-30(22-6-5-18-3-1-2-4-19(18)15-22)25(29-31(26)23-10-14-34-17-23)20-7-11-27-24(16-20)28-21-8-12-33-13-9-21/h1-7,11,15-16,21,23H,8-10,12-14,17H2,(H,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Elan Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of recombinant JNK1 after 60 mins by TR-FRET assay |
Bioorg Med Chem Lett 21: 315-9 (2010)
Article DOI: 10.1016/j.bmcl.2010.11.010 BindingDB Entry DOI: 10.7270/Q24F1R0T |
More data for this Ligand-Target Pair | |