BDBM50334135 (S)-4-(1-(1-(4-cyanobenzyl)indoline-7-carboxamido)ethyl)benzoic acid::CHEMBL1645140

SMILES: C[C@H](NC(=O)c1cccc2CCN(Cc3ccc(cc3)C#N)c12)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=WZKIYFGTKZELEI-KRWDZBQOSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334135 ((S)-4-(1-(1-(4-cyanobenzyl)indoline-7-carboxamido)...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3ccc(cc3)C#N)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23N3O3/c1-17(20-9-11-22(12-10-20)26(31)32)28-25(30)23-4-2-3-21-13-14-29(24(21)23)16-19-7-5-18(15-27)6-8-19/h2-12,17H,13-14,16H2,1H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334135 ((S)-4-(1-(1-(4-cyanobenzyl)indoline-7-carboxamido)...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3ccc(cc3)C#N)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23N3O3/c1-17(20-9-11-22(12-10-20)26(31)32)28-25(30)23-4-2-3-21-13-14-29(24(21)23)16-19-7-5-18(15-27)6-8-19/h2-12,17H,13-14,16H2,1H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair