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BDBM50334223 CHEMBL1641993::N-(1-(3-Bromophenylamino)-4-cyanoisoquinolin-7-yl)-3-morpholinopropanamide

SMILES: Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)CCN4CCOCC4)cc23)c1

InChI Key: InChIKey=DAAAITFDPKRTSZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50334223
PNG
(CHEMBL1641993 | N-(1-(3-Bromophenylamino)-4-cyanoi...)
Show SMILES Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)CCN4CCOCC4)cc23)c1
Show InChI InChI=1S/C23H22BrN5O2/c24-17-2-1-3-18(12-17)28-23-21-13-19(4-5-20(21)16(14-25)15-26-23)27-22(30)6-7-29-8-10-31-11-9-29/h1-5,12-13,15H,6-11H2,(H,26,28)(H,27,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.90E+3n/an/an/an/an/an/a



Chemical Genomics Centre of the Max Planck Society

Curated by ChEMBL


Assay Description
Inhibition of EGFR by HTRF assay


Bioorg Med Chem 19: 429-39 (2011)


Article DOI: 10.1016/j.bmc.2010.11.007
BindingDB Entry DOI: 10.7270/Q22F7NQN
More data for this
Ligand-Target Pair