BDBM50334229 CHEMBL1641997::N-(1-(3-Bromophenylamino)-4-cyanoisoquinolin-7-yl)furan-3-carboxamide

SMILES: Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)c4ccoc4)cc23)c1

InChI Key: InChIKey=AYKBCVLWKNGVRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50334229 (CHEMBL1641997 | N-(1-(3-Bromophenylamino)-4-cyanoi...) Show SMILES Brc1cccc(Nc2ncc(C#N)c3ccc(NC(=O)c4ccoc4)cc23)c1 Show InChI InChI=1S/C21H13BrN4O2/c22-15-2-1-3-16(8-15)25-20-19-9-17(26-21(27)13-6-7-28-12-13)4-5-18(19)14(10-23)11-24-20/h1-9,11-12H,(H,24,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Genomics Centre of the Max Planck Society Curated by ChEMBL					Assay Description Inhibition of EGFR by HTRF assay				Bioorg Med Chem 19: 429-39 (2011) Article DOI: 10.1016/j.bmc.2010.11.007 BindingDB Entry DOI: 10.7270/Q22F7NQN
					More data for this Ligand-Target Pair