BDBM50334339 CHEMBL1358008::N-Benzyl-6-(1-(dimethylamino)butan-2-yloxy)-1-isopropyl-1H-benzo[d]imidazol-4-amine::cid_44143056

SMILES: CCC(CN(C)C)Oc1cc(NCc2ccccc2)c2ncn(C(C)C)c2c1

InChI Key: InChIKey=YHLSWJLBOMKEOE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-9 (Homo sapiens (Human))	BDBM50334339 (CHEMBL1358008 | N-Benzyl-6-(1-(dimethylamino)butan...) Show SMILES CCC(CN(C)C)Oc1cc(NCc2ccccc2)c2ncn(C(C)C)c2c1 Show InChI InChI=1S/C23H32N4O/c1-6-19(15-26(4)5)28-20-12-21(24-14-18-10-8-7-9-11-18)23-22(13-20)27(16-25-23)17(2)3/h7-13,16-17,19,24H,6,14-15H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25M647F
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50334339 (CHEMBL1358008 | N-Benzyl-6-(1-(dimethylamino)butan...) Show SMILES CCC(CN(C)C)Oc1cc(NCc2ccccc2)c2ncn(C(C)C)c2c1 Show InChI InChI=1S/C23H32N4O/c1-6-19(15-26(4)5)28-20-12-21(24-14-18-10-8-7-9-11-18)23-22(13-20)27(16-25-23)17(2)3/h7-13,16-17,19,24H,6,14-15H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of CDK5/P25 GST-fusion protein assessed as substrate histone H1 phosphorylation by scintillation counting				Bioorg Med Chem 19: 359-73 (2011) Article DOI: 10.1016/j.bmc.2010.11.022 BindingDB Entry DOI: 10.7270/Q21G0MJC
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM50334339 (CHEMBL1358008 | N-Benzyl-6-(1-(dimethylamino)butan...) Show SMILES CCC(CN(C)C)Oc1cc(NCc2ccccc2)c2ncn(C(C)C)c2c1 Show InChI InChI=1S/C23H32N4O/c1-6-19(15-26(4)5)28-20-12-21(24-14-18-10-8-7-9-11-18)23-22(13-20)27(16-25-23)17(2)3/h7-13,16-17,19,24H,6,14-15H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM50334339 (CHEMBL1358008 | N-Benzyl-6-(1-(dimethylamino)butan...) Show SMILES CCC(CN(C)C)Oc1cc(NCc2ccccc2)c2ncn(C(C)C)c2c1 Show InChI InChI=1S/C23H32N4O/c1-6-19(15-26(4)5)28-20-12-21(24-14-18-10-8-7-9-11-18)23-22(13-20)27(16-25-23)17(2)3/h7-13,16-17,19,24H,6,14-15H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair