BDBM50334568 CHEMBL1641946::N3-(1-Adamantyl)-1-hexyl-4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxamide

SMILES: CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1

InChI Key: InChIKey=KDTHTYYXAAWQAB-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334568 (CHEMBL1641946 | N3-(1-Adamantyl)-1-hexyl-4-oxo-6-p...) Show SMILES CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:15:16:14.13.19:20,THB:17:16:13:19.18.20,17:18:15.16.21:13,15:14:16.21.17:20| Show InChI InChI=1S/C28H36N2O2/c1-2-3-4-8-11-30-19-24(26(31)15-25(30)23-9-6-5-7-10-23)27(32)29-28-16-20-12-21(17-28)14-22(13-20)18-28/h5-7,9-10,15,19-22H,2-4,8,11-14,16-18H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells after 1 hr				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334568 (CHEMBL1641946 | N3-(1-Adamantyl)-1-hexyl-4-oxo-6-p...) Show SMILES CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:15:16:14.13.19:20,THB:17:16:13:19.18.20,17:18:15.16.21:13,15:14:16.21.17:20| Show InChI InChI=1S/C28H36N2O2/c1-2-3-4-8-11-30-19-24(26(31)15-25(30)23-9-6-5-7-10-23)27(32)29-28-16-20-12-21(17-28)14-22(13-20)18-28/h5-7,9-10,15,19-22H,2-4,8,11-14,16-18H2,1H3,(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	596	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO cells after 1 hr				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334568 (CHEMBL1641946 | N3-(1-Adamantyl)-1-hexyl-4-oxo-6-p...) Show SMILES CCCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 |TLB:15:16:14.13.19:20,THB:17:16:13:19.18.20,17:18:15.16.21:13,15:14:16.21.17:20| Show InChI InChI=1S/C28H36N2O2/c1-2-3-4-8-11-30-19-24(26(31)15-25(30)23-9-6-5-7-10-23)27(32)29-28-16-20-12-21(17-28)14-22(13-20)18-28/h5-7,9-10,15,19-22H,2-4,8,11-14,16-18H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a
Universite£? Lille-Nord de France Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding				J Med Chem 53: 7918-31 (2010) Article DOI: 10.1021/jm100286k BindingDB Entry DOI: 10.7270/Q2BR8SFP
					More data for this Ligand-Target Pair