BDBM50334820 CHEMBL1643153::N-(4-(5-cyano-7-methylbenzo[d]oxazol-2-yl)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide

SMILES: Cc1cc(cc2nc(oc12)-c1ccc(NC(=O)CN2CCN(CC2)c2ccccc2)cc1)C#N

InChI Key: InChIKey=LYPJZEZHGOOSLK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50334820 (CHEMBL1643153 | N-(4-(5-cyano-7-methylbenzo[d]oxaz...) Show SMILES Cc1cc(cc2nc(oc12)-c1ccc(NC(=O)CN2CCN(CC2)c2ccccc2)cc1)C#N Show InChI InChI=1S/C27H25N5O2/c1-19-15-20(17-28)16-24-26(19)34-27(30-24)21-7-9-22(10-8-21)29-25(33)18-31-11-13-32(14-12-31)23-5-3-2-4-6-23/h2-10,15-16H,11-14,18H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated triglyceride transfer by fluorescence-based assay				Bioorg Med Chem Lett 21: 558-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.062 BindingDB Entry DOI: 10.7270/Q2XK8FT1
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50334820 (CHEMBL1643153 | N-(4-(5-cyano-7-methylbenzo[d]oxaz...) Show SMILES Cc1cc(cc2nc(oc12)-c1ccc(NC(=O)CN2CCN(CC2)c2ccccc2)cc1)C#N Show InChI InChI=1S/C27H25N5O2/c1-19-15-20(17-28)16-24-26(19)34-27(30-24)21-7-9-22(10-8-21)29-25(33)18-31-11-13-32(14-12-31)23-5-3-2-4-6-23/h2-10,15-16H,11-14,18H2,1H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated cholesteryl ester transfer by fluorescence-based assay				Bioorg Med Chem Lett 21: 558-61 (2010) Article DOI: 10.1016/j.bmcl.2010.10.062 BindingDB Entry DOI: 10.7270/Q2XK8FT1
					More data for this Ligand-Target Pair