BDBM50335068 2-Amino-5-(4-phenylphenyl)-4-[2-(5-phosphono)furanyl]thiazole::CHEMBL1650208

SMILES: Nc1nc(-c2ccc(o2)P(O)(O)=O)c(s1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=WHPWNUJJJORZSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (FBPase) (Homo sapiens (Human))	BDBM50335068 (2-Amino-5-(4-phenylphenyl)-4-[2-(5-phosphono)furan...) Show SMILES Nc1nc(-c2ccc(o2)P(O)(O)=O)c(s1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H15N2O4PS/c20-19-21-17(15-10-11-16(25-15)26(22,23)24)18(27-19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-11H,(H2,20,21)(H2,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Metabasis Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human liver FBP				J Med Chem 54: 153-65 (2011) Article DOI: 10.1021/jm101035x BindingDB Entry DOI: 10.7270/Q2CN74WJ
					More data for this Ligand-Target Pair