BDBM50335114 3-Benzyl-6-methyl-1-(beta-D-xylopyranosyl)-1H-indole::CHEMBL1650472

SMILES: Cc1ccc2c(Cc3ccccc3)cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c2c1

InChI Key: InChIKey=SPPPLDDFPUBVQT-PLACYPQZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50335114 (3-Benzyl-6-methyl-1-(beta-D-xylopyranosyl)-1H-indo...) Show SMILES Cc1ccc2c(Cc3ccccc3)cn([C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c2c1 |r| Show InChI InChI=1S/C21H23NO4/c1-13-7-8-16-15(10-14-5-3-2-4-6-14)11-22(17(16)9-13)21-20(25)19(24)18(23)12-26-21/h2-9,11,18-21,23-25H,10,12H2,1H3/t18-,19+,20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.03E+3	n/a	n/a	n/a	n/a
Taiwan National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...				J Med Chem 54: 166-78 (2011) Article DOI: 10.1021/jm101072y BindingDB Entry DOI: 10.7270/Q2445NG8
					More data for this Ligand-Target Pair