BDBM50335119 3-Benzyl-7-fluoro-1-(beta-D-xylopyranosyl)-1H-indole::CHEMBL1650477

SMILES: O[C@@H]1CO[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccccc2)c2cccc(F)c12

InChI Key: InChIKey=NBVIIXVODZJQOK-GSEOLPGOSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50335119 (3-Benzyl-7-fluoro-1-(beta-D-xylopyranosyl)-1H-indo...) Show SMILES O[C@@H]1CO[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccccc2)c2cccc(F)c12 |r| Show InChI InChI=1S/C20H20FNO4/c21-15-8-4-7-14-13(9-12-5-2-1-3-6-12)10-22(17(14)15)20-19(25)18(24)16(23)11-26-20/h1-8,10,16,18-20,23-25H,9,11H2/t16-,18+,19-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.82E+3	n/a	n/a	n/a	n/a
Taiwan National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...				J Med Chem 54: 166-78 (2011) Article DOI: 10.1021/jm101072y BindingDB Entry DOI: 10.7270/Q2445NG8
					More data for this Ligand-Target Pair