BDBM50335133 4-Chloro-3-(4-fluorobenzyl)-1-(beta-D-xylopyranosyl)-1H-indole::CHEMBL1650489

SMILES: O[C@@H]1CO[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(F)cc2)c2c(Cl)cccc12

InChI Key: InChIKey=QPMYOINRLFFLLW-GSEOLPGOSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50335133 (4-Chloro-3-(4-fluorobenzyl)-1-(beta-D-xylopyranosy...) Show SMILES O[C@@H]1CO[C@H]([C@H](O)[C@H]1O)n1cc(Cc2ccc(F)cc2)c2c(Cl)cccc12 |r| Show InChI InChI=1S/C20H19ClFNO4/c21-14-2-1-3-15-17(14)12(8-11-4-6-13(22)7-5-11)9-23(15)20-19(26)18(25)16(24)10-27-20/h1-7,9,16,18-20,24-26H,8,10H2/t16-,18+,19-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a
Taiwan National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as sodium-dependent [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scint...				J Med Chem 54: 166-78 (2011) Article DOI: 10.1021/jm101072y BindingDB Entry DOI: 10.7270/Q2445NG8
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