BDBM50335326 CHEMBL1651491::N-(4-((4-(1H-pyrazol-3-ylamino)-1-oxophthalazin-2(1H)-yl)methyl)phenyl)acetamide

SMILES: CC(=O)Nc1ccc(Cn2nc(Nc3ccn[nH]3)c3ccccc3c2=O)cc1

InChI Key: InChIKey=MOWOODVZLKWUAO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50335326 (CHEMBL1651491 | N-(4-((4-(1H-pyrazol-3-ylamino)-1-...) Show SMILES CC(=O)Nc1ccc(Cn2nc(Nc3ccn[nH]3)c3ccccc3c2=O)cc1 Show InChI InChI=1S/C20H18N6O2/c1-13(27)22-15-8-6-14(7-9-15)12-26-20(28)17-5-3-2-4-16(17)19(25-26)23-18-10-11-21-24-18/h2-11H,12H2,1H3,(H,22,27)(H2,21,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora A by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50335326 (CHEMBL1651491 | N-(4-((4-(1H-pyrazol-3-ylamino)-1-...) Show SMILES CC(=O)Nc1ccc(Cn2nc(Nc3ccn[nH]3)c3ccccc3c2=O)cc1 Show InChI InChI=1S/C20H18N6O2/c1-13(27)22-15-8-6-14(7-9-15)12-26-20(28)17-5-3-2-4-16(17)19(25-26)23-18-10-11-21-24-18/h2-11H,12H2,1H3,(H,22,27)(H2,21,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Inhibition of Aurora B by ELISA				J Med Chem 54: 312-9 (2011) Article DOI: 10.1021/jm101346r BindingDB Entry DOI: 10.7270/Q29P32MB
					More data for this Ligand-Target Pair