BDBM50335474 (S)-4-(3-(2-((1-(2-(4-((4-(1-acetyl-6-biphenyl-4-ylcarboxamido-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-4-yl)phenoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)-1H-1,2,3-triazol-4-yl)methylamino)-2-oxoethylamino)phenyl)-5-amino-N-tert-butyl-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide::CHEMBL1651829
SMILES: CSc1nc(-c2cccc(NCC(=O)NCc3cn(CCn4cc(COc5ccc(cc5)[C@]5(C)CC(C)(C)N(C(C)=O)c6ccc(NC(=O)c7ccc(cc7)-c7ccccc7)cc56)nn4)nn3)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C
InChI Key: InChIKey=ONPNZMGRFBOPLV-WMNDHARXSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human)) | BDBM50335474 ((S)-4-(3-(2-((1-(2-(4-((4-(1-acetyl-6-biphenyl-4-y...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Agonist activity at human LH receptor expressed in CHO-K1 cells assessed as stimulation of luciferase activity by CRE-driven luciferase reporter gene... | ACS Med Chem Lett 2: 85-89 (2011) Article DOI: 10.1021/ml100229v BindingDB Entry DOI: 10.7270/Q2RV0NZG | |||||||||||
More data for this Ligand-Target Pair |