BDBM50335871 3-(1-(4-(4-chloronaphthalen-1-ylamino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)-6-hydroxy-2-phenylbenzofuran-5-carboxylic acid::CHEMBL1650894

SMILES: OC(=O)c1cc2c(-c3cn(CCCC(=O)Nc4ccc(Cl)c5ccccc45)nn3)c(oc2cc1O)-c1ccccc1

InChI Key: InChIKey=HIENJFMWBLFVEQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335871   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50335871 (3-(1-(4-(4-chloronaphthalen-1-ylamino)-4-oxobutyl)...) Show SMILES OC(=O)c1cc2c(-c3cn(CCCC(=O)Nc4ccc(Cl)c5ccccc45)nn3)c(oc2cc1O)-c1ccccc1 Show InChI InChI=1S/C31H23ClN4O5/c32-23-12-13-24(20-10-5-4-9-19(20)23)33-28(38)11-6-14-36-17-25(34-35-36)29-22-15-21(31(39)40)26(37)16-27(22)41-30(29)18-7-2-1-3-8-18/h1-5,7-10,12-13,15-17,37H,6,11,14H2,(H,33,38)(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant LyP assessed as hydrolysis of DiFMUP				J Med Chem 54: 562-71 (2011) Article DOI: 10.1021/jm101004d BindingDB Entry DOI: 10.7270/Q2N016T4
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