null

SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O

InChI Key: InChIKey=SRZRYXSPNGRFHP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50336007 (6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:18| Show InChI InChI=1S/C18H13ClF3NO5S/c1-29(26,27)23-12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(24)25)16(18(20,21)22)28-15(10)13/h2-8,16,23H,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human COX2				Bioorg Med Chem Lett 21: 993-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.023 BindingDB Entry DOI: 10.7270/Q2QR4XDS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50336007 (6-chloro-8-(4-(methylsulfonamido)phenyl)-2-(triflu...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc(Cl)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O |c:18| Show InChI InChI=1S/C18H13ClF3NO5S/c1-29(26,27)23-12-4-2-9(3-5-12)13-8-11(19)6-10-7-14(17(24)25)16(18(20,21)22)28-15(10)13/h2-8,16,23H,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human COX1				Bioorg Med Chem Lett 21: 993-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.023 BindingDB Entry DOI: 10.7270/Q2QR4XDS
					More data for this Ligand-Target Pair