BDBM50336024 2-morpholino-N-(5-(2-morpholino-4-oxo-4H-chromen-8-yl)biphenyl-2-yl)acetamide::CHEMBL1669170

SMILES: O=C(CN1CCOCC1)Nc1ccc(cc1-c1ccccc1)-c1cccc2c1oc(cc2=O)N1CCOCC1

InChI Key: InChIKey=KJQZPWWZMYOHNZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50336024 (2-morpholino-N-(5-(2-morpholino-4-oxo-4H-chromen-8...) Show SMILES O=C(CN1CCOCC1)Nc1ccc(cc1-c1ccccc1)-c1cccc2c1oc(cc2=O)N1CCOCC1 Show InChI InChI=1S/C31H31N3O5/c35-28-20-30(34-13-17-38-18-14-34)39-31-24(7-4-8-25(28)31)23-9-10-27(26(19-23)22-5-2-1-3-6-22)32-29(36)21-33-11-15-37-16-12-33/h1-10,19-20H,11-18,21H2,(H,32,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of DNA-PK				Bioorg Med Chem Lett 21: 966-70 (2011) Article DOI: 10.1016/j.bmcl.2010.12.047 BindingDB Entry DOI: 10.7270/Q2G73F0W
					More data for this Ligand-Target Pair