BDBM50336434 1-(1H-Indol-2-yl)-2-pyridin-3-yl-ethanone::CHEMBL1668301

SMILES: O=C(Cc1cccnc1)c1cc2ccccc2[nH]1

InChI Key: InChIKey=FCWVNIGLANOQIG-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50336434 (1-(1H-Indol-2-yl)-2-pyridin-3-yl-ethanone | CHEMBL...) Show SMILES O=C(Cc1cccnc1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C15H12N2O/c18-15(8-11-4-3-7-16-10-11)14-9-12-5-1-2-6-13(12)17-14/h1-7,9-10,17H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Uncompetitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 4...				Eur J Med Chem 46: 3058-65 (2011) Article DOI: 10.1016/j.ejmech.2011.02.049 BindingDB Entry DOI: 10.7270/Q2F19029
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50336434 (1-(1H-Indol-2-yl)-2-pyridin-3-yl-ethanone | CHEMBL...) Show SMILES O=C(Cc1cccnc1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C15H12N2O/c18-15(8-11-4-3-7-16-10-11)14-9-12-5-1-2-6-13(12)17-14/h1-7,9-10,17H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibition of human IDO activity by spectrophotometry				Bioorg Med Chem 19: 1550-61 (2011) Article DOI: 10.1016/j.bmc.2010.12.032 BindingDB Entry DOI: 10.7270/Q27M087F
					More data for this Ligand-Target Pair