BDBM50336447 1-(7-methoxy-1H-indol-2-yl)-2-pyridin-3-yl-ethanone::CHEMBL1668316

SMILES: COc1cccc2cc([nH]c12)C(=O)Cc1cccnc1

InChI Key: InChIKey=AJBZILMEHFPPJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50336447 (1-(7-methoxy-1H-indol-2-yl)-2-pyridin-3-yl-ethanon...) Show SMILES COc1cccc2cc([nH]c12)C(=O)Cc1cccnc1 Show InChI InChI=1S/C16H14N2O2/c1-20-15-6-2-5-12-9-13(18-16(12)15)14(19)8-11-4-3-7-17-10-11/h2-7,9-10,18H,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Inhibition of human IDO activity by spectrophotometry				Bioorg Med Chem 19: 1550-61 (2011) Article DOI: 10.1016/j.bmc.2010.12.032 BindingDB Entry DOI: 10.7270/Q27M087F
					More data for this Ligand-Target Pair