BDBM50336500 (E)-N-(9-(2-(ethoxycarbonyl)phenyl)-6-(ethylamino)-2,7-dimethyl-3H-xanthen-3-ylidene)ethanaminium chloride::CHEMBL402140::[9-(2-ethoxycarbonyl-phenyl)-6-ethylamino-2,7-dimethyl-xanthen-(3E)-ylidene]-ethyl-ammonium; chloride::rhodamine 6G
SMILES: CCNc1cc2oc3c\c(=N/CC)c(C)cc3c(-c3ccccc3C(=O)OCC)c2cc1C
InChI Key: InChIKey=IWWWBRIIGAXLCJ-BGABXYSRSA-N
Data: 3 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Multidrug resistance protein mdtK (Escherichia coli (strain K12)) | BDBM50336500 ((E)-N-(9-(2-(ethoxycarbonyl)phenyl)-6-(ethylamino)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a |
Iowa State University Curated by ChEMBL | Assay Description Binding affinity to purified detergent-solubilized Escherichia coli K-12 multidrug efflux protein YdhE by equilibrium dialysis method | Antimicrob Agents Chemother 52: 3052-60 (2008) Article DOI: 10.1128/AAC.00475-08 BindingDB Entry DOI: 10.7270/Q2BC3ZT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance protein mdtK (Escherichia coli (strain K12)) | BDBM50336500 ((E)-N-(9-(2-(ethoxycarbonyl)phenyl)-6-(ethylamino)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a |
Iowa State University Curated by ChEMBL | Assay Description Binding affinity to Escherichia coli K-12 multidrug efflux protein YdhE expressed in Escherichia coli AG100AX in presence of 0.02% DDM surfactant by ... | Antimicrob Agents Chemother 52: 3052-60 (2008) Article DOI: 10.1128/AAC.00475-08 BindingDB Entry DOI: 10.7270/Q2BC3ZT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AcrAB-TolC (Escherichia coli) | BDBM50336500 ((E)-N-(9-(2-(ethoxycarbonyl)phenyl)-6-(ethylamino)...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | 8.4 | n/a |
Iowa State University Curated by ChEMBL | Assay Description Binding affinity to Escherichia coli K-12 multidrug efflux protein AcrB at pH 8.4 by equilibrium dialysis method | Antimicrob Agents Chemother 52: 3052-60 (2008) Article DOI: 10.1128/AAC.00475-08 BindingDB Entry DOI: 10.7270/Q2BC3ZT0 | |||||||||||
More data for this Ligand-Target Pair |