BDBM50336510 7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1,10-dihydropyrano[4,3-b]chromene-9-carboxylic acid::CHEMBL1673300
SMILES: COC1OC(C)=Cc2oc3cc(O)c(O)c(C(O)=O)c3c(=O)c12
InChI Key: InChIKey=CBEPLTZXYMLBAP-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50336510 (7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1,10-dihyd...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair |