BDBM50337150 (RS)-1-amino-2-cyclohexylethylphosphonic acid::CHEMBL1673062
SMILES: NC(CC1CCCCC1)P(O)(O)=O
InChI Key: InChIKey=VWVYLBIQWASACG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50337150 ((RS)-1-amino-2-cyclohexylethylphosphonic acid | CH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 5.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Inhibition of pig kidney microsomal aminopeptidase N | Antimicrob Agents Chemother 52: 3221-8 (2008) Article DOI: 10.1128/AAC.01327-07 BindingDB Entry DOI: 10.7270/Q2S75GMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human)) | BDBM50337150 ((RS)-1-amino-2-cyclohexylethylphosphonic acid | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate | J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |