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SMILES: Cc1cc(cc2nc(oc12)-c1ccc(cc1)C(=O)CCN1CCN(CC1)c1ccc(cc1)C(F)(F)F)C#N

InChI Key: InChIKey=PNKGLAMXBOQUHR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337156   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50337156
PNG
(7-methyl-2-(4-(3-(4-(4-(trifluoromethyl)phenyl)pip...)
Show SMILES Cc1cc(cc2nc(oc12)-c1ccc(cc1)C(=O)CCN1CCN(CC1)c1ccc(cc1)C(F)(F)F)C#N
Show InChI InChI=1S/C29H25F3N4O2/c1-19-16-20(18-33)17-25-27(19)38-28(34-25)22-4-2-21(3-5-22)26(37)10-11-35-12-14-36(15-13-35)24-8-6-23(7-9-24)29(30,31)32/h2-9,16-17H,10-15H2,1H3
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Similars
Article
PubMed
n/an/a 2.05E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CETP

Bioorg Med Chem Lett 21: 1890-5 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.090
BindingDB Entry DOI: 10.7270/Q2NG4QW6
More data for this
Ligand-Target Pair